Egg Donation: If you are older, especially if you’re over 42, and have not succeeded with other therapies, or if you have premature ovarian failure (POF), also known as early menopause, your treatment options are limited. Egg donation, which involves the use of eggs donated by another woman who is typically in her 20s or early 30s, is highly successful. The high success rate with egg donation confirms that egg quality associated with age is the primary barrier to pregnancy in older women. If you are over 40, your chance of successful pregnancy is much higher in IVF cycles using donor eggs, but many couples or single women in their early 40s will choose to accept the lower chance of become pregnant and use their own eggs. By age 43, the chance of becoming pregnant through IVF is less than 5%, and by age 45, use of donor eggs is the only reasonable alternative. In an egg donation cycle, the woman receiving the donated eggs is referred to as the “recipient.” The egg donor receives fertility medications to stimulate the production of multiple eggs in her ovaries. At the same time, the egg recipient is given hormone therapy to prepare her uterus to receive the fertilized eggs (embryos). After the eggs are obtained from the donor, they are fertilized in the laboratory with sperm from the recipient’s partner. Several days after fertilization, the embryos are transferred to the recipient’s uterus. Any embryos that are not transferred may be frozen (cryopreserved) for a future cycle. Donor-egg IVF offers a woman an opportunity to experience pregnancy, birth, and motherhood. The child, however, will not be genetically related to her but will be genetically related to the father and the egg donor. Many programs recommend counseling so that all parties in a donor-egg agreement understand the ethical, legal, psychological, and social issues involved. Because success depends heavily upon the quality of eggs that are donated, women in their 20s with proven fertility are ideal donors. Fertility Preservation: Women who wish to delay childbearing until their late 30s or early 40s may consider methods of fertility preservation such as freezing of embryos after IVF or retrieving and freezing eggs for later use. The success of embryo freezing (cryopreservation) is well established, but it requires that the woman have a male partner or use donor sperm. Egg freezing for preservation of fertility is a new technology that shows promise for success. Age remains a problem faced by women interested in using elective egg freezing. As the age of women undergoing egg freezing increases, the outcomes of assisted reproductive technology cycles utilizing their frozen eggs become less favorable. Best Fertility Care Centre, Advanced Fertility Care Centre, Ashwini Hospital Moondrumavadi K.Pudur Madurai -07 , Maternal & Child Health Care .