What are some possible causes of female infertility? Getting pregnant and carrying a pregnancy to term are actually very complicated processes. Many things can go wrong during these processes to lead to infertility. For this reason, the following list includes only some of the common causes of infertility in females; it is not meant to be all-inclusive. A woman who is having difficulty getting pregnant or carrying a pregnancy to term should talk with her health care provider about possible treatments. FAILURE TO OVULATE: The most common overall cause of female infertility is the failure to ovulate, which occurs in 40% of women with infertility issues.1 Not ovulating can result from several causes, such as: Ovarian or gynecological conditions, such as primary ovarian insufficiency (POI) or polycystic ovary syndrome (PCOS) Aging, including "diminished ovarian reserve, " which refers to a low number of eggs in a woman's ovaries due to normal aging Endocrine disorders, such as thyroid disease or problems with the hypothalamus, which affect the hormones produced by the body so that there might be too much or too little of a hormone or group of hormones Lifestyle and environmental factors Problems with the menstrual cycle, the process that prepares the female body for pregnancy, can lead to infertility. The menstrual cycle includes several phases, and problems at any one of the stages can lead to difficulty getting pregnant or to infertility. Best fertility care center, Advanced Fertility Care Center , Ashwini Hospital Moondrumavadi Madurai -07 .